All that said, one of the biggest risk factors for osteoporosis is out of your hands—it's your chromosomal gender. Roughly 80 percent of the 10 million people who have it are women. And women are about twice as likely to break a bone because of osteoporosis than men.
But there's more. Estrogen, among other things, helps protect bones. So, when menopause occurs, there's a marked increase in the risk for bone loss.