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WATCH: 7-Year-Old Makes Heartfelt Plea to Save His Dying Sister

Four-year-old Eliza O'Neill and her 7-year-old brother, Beckham, have been more or less inseparable since Eliza was born. Through the good and the bad, they have been the best of friends.

The bad came on July 17, 2013, when little Eliza was diagnosed with a rare condition called Sanfilippo syndrome. It will eventually cause her to lose her ability to speak and even walk; and most heartbreaking of all, it will also eventually claim her life.

But there is one spot of hope for the O'Neill family: A gene therapy trial, due to take place at Nationwide Children's Hospital later this year, could be the key to saving little Eliza and other kids just like her. But that trial will cost a whopping $2.5 million just to fund, and right now, the hospital has not met its goal.

That's why the O'Neills are pulling out all the stops in an effort to raise as much money as possible for the trial. And Beckham has made sure to be a big part of their campaign. In a video posted to the family's GoFundMe page, the little boy pleads for strangers to donate whatever they have. "We really need you to help us get my sister medicine quickly ... I mean immediately," he says.

It's a moving thing to see, something that his dad, Glenn, and mom, Cara, can't help but cry over every time they watch. "And yet it is so hopeful and encouraging at the same time," dad, Glenn, said.

So far, Beckham's video has touched several other hearts, too. The page has raised more than $600,000 and counting.

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