Doctors at the Cleveland Clinic surgically removed the donated organ on Wednesday, after the 26-year-old recipient, identified only as Lindsey, developed complications.
The transplant team said they will study why the organ was rejected. Eileen Sheil, spokesperson for the clinic, said the patient suddenly developed a serious and unspecified complication on Tuesday. Doctors will analyze the removed organ to better understand what happened.
The New York Times reported that the complications started a day after the surgical team and Lindsey appeared a press conference, saying a biopsy indicated the body was accepting the organ.
Despite disappointment from the rejection, the hospital officials said Lindsey is doing well. She and her husband Blake released the following statement:
"I just wanted to take a moment to express my gratitude towards all of my doctors. They acted very quickly to ensure my health and safety. Unfortunately, I did lose the uterus to complications. However, I am doing OK and appreciate all of your prayers and good thoughts."
The transplant, the first of 10 experimental surgeries for women who can't bear children due to missing or compromised wombs, was the first of its kind in North America. Doctors in Sweden performed the first of several successful transplants in 2014. Uterine transplants in that country have resulted in five live births to women who would have otherwise not been able to carry a child to term.